Indian Journal of Human Genetics
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CASE REPORT
Year : 2011  |  Volume : 17  |  Issue : 3  |  Page : 238-240

Octaploidy in idiopathic thrombocytopenic purpura


Department of Tranplant Immunology, Molecular Biology and Transfusion Medicine, Apollo Hospitals, New Delhi, India

Correspondence Address:
Mohit Chowdhry
Transplant Immunology, Molecular Biology and Transfusion Medicine, Apollo Hospitals, Sarita Vihar, Delhi Mathura Road, New Delhi - 110 076
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-6866.92091

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We report a case of an elderly 68-year-old male who presented in our hospital with chief complaints of petechial rashes and ecchymosis over extremities and bleeding from the oral cavity since 3-4 days prior to hospitalization. He saw a physician before coming to our hospital and received one dose of IV methylprednisolone and oral wysolone. He had come to our hospital for further management. Bone marrow karyotyping was done and chromosomal analysis revealed two cell lines. Eighty percent of the cells analyzed revealed apparently normal male karyotype. However, 20% cells analyzed revealed a total of 184 chromosomes, suggesting octaploidy.


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