Discovery and Therapeutic Promise of Selective Androgen Receptor Modulators

  Figure 3.   Figure 3.
Figure 3.

Tissue-selective pharmacologic activity of S-4. A. Male rats were castrated and treated for 14 consecutive days with S-4. S-4 potently stimulates muscle growth, but is unable to maintain prostate size. Adapted from J. Pharmacol. Exp. Therap.304,1334 (2005). B. Testosterone stimulates muscle and prostate growth to the same extent.

This Article

  1. MI June 2005 vol. 5 no. 3 173-188