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S-Nitrosylation Signaling in Cell Biology
Figure 2.
Cu/Zn mutations accelerate the decomposition of GSNO. Decomposition of 7 μM GSNO in the presence of 125 μM glutathione and 10 μM WT SOD (squares), 10 μM A4V SOD (diamonds), 10 μM G37R SOD (triangles) or 0 μM SOD control (circles) in 10 mM PBS at pH 7.4 and 37oC. GSNO content analyzed by ( A) chemiluminenscence or ( B) liquid chromatograpy–mass spectrometry (LC-MS). Reprinted with permission (28).
