DNA DAMAGE-INDUCED MUTAGENESIS

  Figure 1.
Figure 1.

Two mechanisms of damage tolerance. Template switching is error-free, because it avoids copying the damaged site of the DNA template. Lesion bypass directly uses damaged DNA as template. Consequently, mutations (shown as a purple squares) are often generated opposite the lesion site.

This Article

  1. MI December 2001 vol. 1 no. 5 269-281